Pop a pill that makes you smarter. Sounds like a Hollywood movie plot, but the decades-long search for an effective “smart pill” might have hit paydirt.
Modafinil, which is known by its brand name Provigil, is a wakefulness-promoting smart pill used to treat sleep disorders such as narcolepsy. It also is prescribed for shift work sleep disorder and obstructive sleep apnea.
Increases Dopamine Levels
Modafinil, like cocaine and MDMA, is a dopamine reuptake inhibitor. Modalert Tablets block the brain’s nerve cells from reabsorbing dopamine after it’s been released into synapses, so the leftover dopamine stays in the gap between the two nerve cells and gives you that “buzz.”
The smart pill is used to treat narcolepsy, shift work sleep disorder, and obstructive sleep apnea. But it’s also a popular cognitive enhancer among high school and college students, professionals working late into the night, and people who need to focus for extended periods of time.
Studies have found that it boosts higher-order cognitive functions such as memory, flexibility of thought, and decision-making. It also improves mood and decreases lethargy in people with Parkinson’s. And it’s much less risky than caffeine or other stimulants, which can cause heart problems and addiction.
Increases Serotonin Levels
In the current culture of competition and overwork, many people turn to Modafinil 200 mg in order to power through their 14-hour work days. While this may help you get the job done. Instead, try to focus on getting enough sleep.
Modafinil is a stimulant that has been shown to increase wakefulness in sleep-deprived individuals. It works by inhibiting the reuptake of dopamine and increasing extracellular levels of the chemical. Modafinil also increases the activity of glutamate and GABA. The smart pill has been use to optimize performance in astronauts aboard the International Space Station, improving circadian rhythm disruptions and compensating for reduce sleep. It is also sometimes take by doctors after a night of sleepless work to enhance their cognitive performance.
Increases GABA Levels
Modafinil increases levels of GABA, the brain’s inhibitory neurotransmitter. This helps to slow down the activity of neurons and reduce anxiety levels. It has also been show to improve working memory.
Modafinil’s wake-promoting effects match those of stimulants like amphetamine and methylphenidate but differ in their cognitive enhancements. It boosts brain power but doesn’t increase creativity or flexibility of thinking. It does help people who normally have low performance in these tasks.
In one study with narcolepsy and shift-work sleep disorder patients, a subgroup analysis found that the smart pill enhanced cognition only in those who had an initial fatigue scale score of less than 8. This indicates that it does not make people smarter, just more alert. It is important to follow the directions on your prescription label and to ask your doctor or pharmacist any questions about it.
Increases Glutamate Levels
Modafinil increases glutamate levels in the brain, and may also cause alterations to NMDA reuptake or NMDA receptor activity (Mizenberg and Carter). The smart pill interacts with adrenergic mechanisms to increase synaptic norepinephrine and dopamine levels. It also enhances the levels of glutamate in the thalamus, hypothalamus, and striatum and reduces cortical GABA.
Stimulants can be dangerous and addictive, even at low doses, especially if taken for long periods of time. Many white-collar workers illegally obtain Modafinil and its close relative armodafinil without a prescription on the black market, which is dangerous because the pills often contain impurities or have inaccurate dosing. Modafinil can decrease sleepiness, but it does not cure narcolepsy or obstructive sleep apnea/hypopnea syndrome. It is important to continue to follow your doctor’s advice for getting enough sleep.
Increases Oxytocin Levels
In a study that included both human and animal subjects, modafinil was find to increase oxytocin levels, which is know to be a “nootropic” that can boost cognitive performance. Oxytocin is produce by certain brain regions, including the prefrontal cortex and hypothalamus.
Modafinil can also be use to improve mood and memory. It can help those suffering from depression and ADHD. It can even reduce fatigue and irritability caused by narcolepsy, shift work sleep disorder, or jet lag.
Unlike other stimulants, which can be addictive, modafinil has minimal side effects and does not affect the heart rate or blood pressure. However, it is important to get enough rest and avoid excessive stress to maintain a healthy life. Instead of relying on modafinil, make a change to your lifestyle so that you can achieve the tasks you need without feeling overwhelmed.