Looking to learn how to get blood out of sheets? Begin by soaking the affected area in cold water. Gently blot with a clean cloth to lift the stain. For tougher stains, apply hydrogen peroxide or a mixture of baking soda and water directly to the spot. Let it sit for a few minutes before rinsing. Wash the sheets in cold water with enzyme-based detergent. Avoid hot water as it can set the stain. Air dry and check before machine drying.