Southern Blotting: Molecular Biology Technique for Detecting Specific DNA Sequences

The Southern Blotting is a molecular biology technique used to detect specific DNA sequences in denatured, fragmented DNA samples. It enables researchers to determine whether a DNA sample contains a specific DNA sequence such as a particular gene or genetic mutation.

Blotting is a highly valuable molecular technique that enables analysis of genomic DNA through detection of specific sequences. Advances continue improving its versatility, sensitivity, and combination with other methods like PCR, hybridization arrays, and next-generation sequencing.

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