The completion of human genome sequencing and the elucidation of the molecular pathways that are critical in the disease molecule interaction have offered an unprecedented opportunity and growth for the development of nucleic acid-based therapeutics. However, to keep with the manufacturing and development of such therapies, the pharmaceutical companies have established partnerships with the contract development and manufacturing company (CDMO) which are the viable alternatives to the in-house development of the drugs. Moreover, the success of the respective business model has also led these CDMOs to become an integral part of such pharmaceutical companies’ value chain.
The increasing willingness to outsource drug development to the CDMOs, and the rising need for pharmaceuticals have resulted in the expansion of the global market for nucleic acid therapeutics CDMO.
The global nucleic acid therapeutics CDMO market is expected to reach $4,463.7 Million by 2030, with a CAGR of 11.09 % during the forecast period 2021-2030. Factors driving the growth of the global nucleic acid therapeutics CDMO market are accelerating shift of the pharmaceutical market toward innovative biologic and cell and gene therapy products, reduction in overall manufacturing cost at CDMOs, and rising approvals of nucleic acid therapeutics.
Market Segmentation
The BIS Research report on the nucleic acid therapeutics CDMO market segments the market on the basis of:
• Product – Standard Nucleic Acid, Micro-Scale Nucleic Acid, Large-Scale Nucleic Acid, Custom Nucleic Acid, Modified Nucleic Acid, Primers, Probes, Other Nucleic Acid, Other Services
• Chemical Synthesis – Solid-Phase Oligonucleotide Synthesis, Liquid-Phase Oligonucleotide Synthesis
• Technology – Column-Based Method, Microarray-Based Method
• End User – Pharmaceutical Companies, Academic Research Institute, Diagnostic Laboratories
Regional Segmentation
• North America – U.S., Canada
• Europe – Germany, U.K., France, Italy, Spain, Rest-of-Europe
• Asia-Pacific – Japan, China, India, Australia, Rest-of-Asia-Pacific
• Rest-of-the-World
Competitive Landscape
The exponential rise in the application of nucleic acid therapeutics CDMO market on the global level has created a buzz among companies to invest in the manufacturing of nucleic acid-based therapies. In the past five years (July 2017-July 2021), the nucleic acid therapeutics CDMO market witnessed approximately 31 notable key developments. These included one product launch, two regulatory and legal activities, three mergers and acquisitions, 24 synergistic developments (partnerships, collaborations, agreements, and business expansion activities).
On the basis of region, North America holds the largest share within the nucleic acid therapeutics CDMO manufacturing due to improved healthcare infrastructure, rise in per capita income, and improvised reimbursement policies in the region. Apart from this, Latin America and the Asia-Pacific region are anticipated to grow at the fastest CAGR during the forecast period of 2021-2030.
Global Nucleic Acid Therapeutics CDMO Market, Market Dynamics
Rising Approvals of Nucleic Acid Therapeutics
In the past decade, there has been a vast increase in the amount of gene sequence information that has the potential to revolutionize the way diseases are categorized and treated. Traditional diagnoses, largely anatomical or descriptive in nature, are likely to be superseded by the molecular characterization of the disease. The fact that certain genes drive key disease processes will also enable the rational design of gene-specific therapeutics. Antisense oligonucleotides represent a technology that can play multiple roles in this process. Further, at present, there are 16 nucleic acid therapies approved by the FDA and EMA and many more in the pipeline implying the reliance and acceptance over the usage of such therapies in the market.
Key Companies Profiled
Agilent Technologies, Inc., Ajinomoto Co. Inc., Bachem Holding AG, Biospring GmbH, Corden Pharma International, Danaher Corporation, Guangzhou Ruibo Biotechnology Co., Ltd., KNC Laboratories Co., Ltd., LGC Limited, Merck KGaA, Nippon Shokubai Co., Ltd., Nitto Denko Avecia Inc., QIAGEN N.V., ST Pharm Co Ltd, Sumitomo Chemical Co., Ltd., Syngene International Limited, Thermo Fisher Scientific Inc., Wuxi AppTec, Yamasa Corporation
Key Questions Answered in this Report:
• What are the different types of nucleic acid therapies available in the global nucleic acid therapeutics CDMO market?
• What are the key development strategies implemented by the key players to stand out in this global nucleic acid therapeutics CDMO market?
• What are the manufacturing locations of the key companies within the global nucleic acid therapeutics CDMO market?
• What are the various manufacturing technologies within the global nucleic acid therapeutics CDMO market?
• How have the strategic collaborations among the key players provided a push to product development within the global nucleic acid therapeutics CDMO market?
• Which are the leading companies that are dominating the global nucleic acid therapeutics CDMO market?
• Based on the product type, which therapy in the global nucleic acid therapeutics CDMO market is anticipated to witness a massive rise in demand during the forecast period?
• How is each segment of the global nucleic acid therapeutics CDMO market expected to grow during the forecast period, and what revenue is expected to be generated by each of these segments by the end of 2030?
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The report scope constitutes an in-depth study of the global nucleic acid therapeutics CDMO market, including a thorough analysis of the types of products offered. The study also presents a detailed analysis of the market dynamics and the estimation of the market size, including a forecast till 2030. The scope of this report is focused on different types of product chemical synthesis methods, end-users, regions, and country-wise analysis.
