In Vivo Toxicology Market worth $6.6 billion by 2025

The growing focus on carcinogenic toxicity tests for drugs is likely to propel the use of animal models for in vivo toxicology testing.

The report "In Vivo Toxicology Market by Product (Animal Models, Reagents Kits), Test Type (Chronic, Sub-acute), Toxicity Endpoints (Systemic, Immunotoxicity), Testing Facility (Outsourced, In-house), End User (Academic Research Institute, CROs) - Forecast to 2025" The global in vivo toxicology market size is projected to reach USD 6.6 billion by 2025, at a CAGR of 5.5% between 2020 and 2025.

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Market growth is driven largely by the increasing pharmaceutical RD activities, innovations in animal models, the development of exclusive in vivo toxicology tests, and the increasing demand for personalized medicine

Consumables accounted for the largest share in the in vivo toxicology market in 2019.

Based on the product, the in vivo toxicology market is categorized into instruments and consumables. The consumables segment is further categorized into animal models and reagents kits. Animal models is sub segmented into mice, rat and other animals. The consumables segment accounted for the largest share of the in vivo toxicology market in 2019. The widespread use of reagents kits in research activities, increase in funds for research projects, and their extensive application in the in vivo toxicology studies are fueling the growth of this segment

Chronic test type accounted for the largest share in the in vivo toxicology market in 2019

Based on test type, the global in vivo toxicology market is segmented into acute, sub-acute, sub-chronic, and chronic test type. The chronic test type segment is expected to dominate the market during the forecast period. In 2019, the chronic test type segment held the largest share of  the market, followed by sub-chronic test type.Increasing research on drugs used for longer-duration therapy such as anti-cancer, anti-convulsive, anti-arthritis, and anti-hypertensives drives the growth of the chronic test type market.

Outsourced testing facilities accounted for the largest share in the in vivo toxicology market in 2019

Based on the testing facility, the global in vivo toxicology market is segmented into outsourced testing facilities and in-house testing facilities. The outsourced testing facilities segment is expected to dominate the market, by testing facility, over the forecast period. In 2019, the outsourced testing facilities segment held the largest share  of the global in vivo toxicology market. The large share of this segment is attributed to the increasing RD investments and cost-saving strategies of pharmaceutical, biopharmaceutical, and medical devices companies, resulting in increased outsourcing of services to CROs

Academic and research institutes  accounted for the largest share the in vivo toxicology market in 2019

Based on the end user, the global in vivo toxicology market has been broadly segmented into academic research institutes, pharmaceutical biotechnology companies, contract research organizations, and other end users (cosmetic companies and food laboratories). The academic and research institutes segment accounted for the largest share of the in vivo toxicology market in 2019. The increasing number of research activities in the field of in vivo toxicology and funding to the academic and research institutes to conduct in vivo toxicology research are the factors responsible for the largest share of the segment

North America accounted for the largest share of the in vivo toxicology market in 2019.

Based on the region, the global in vivo toxicology market is segmented into North America, Europe, the Asia Pacific, Latin Ametica and Middle East Africa. In 2019, North America accounted for the largest share of the in vivo toxicology market. The large share of the North America region can be attributed to the presence of major players operating in the in vivo toxicology market in the US, growing biomedical research in the US, and rising preclinical activities by CROs and pharmaceutical companies in the region.

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The major players operating in this market are by Charles River Laboratories (US), The Jackson Laboratory (US), Envigo (US), Taconic Biosciences, Inc. (US), and JANVIER LABS (France), Thermo Fisher Scientific (US), Danaher Corporation (US), Waters Corporation (US), Agilent Technologies (US), Shimadzu Corporation (Japan), Bruker Corporation (US), PerkinElmer (US). Other prominent players include Merck KGaA (Germany), GE Healthcare (US), and Bio-Rad Laboratories (US), genOway (France), Cyagen Biosciences (US), GVK BIO (India), PolyGene (Switzerland), Crown Biosciences (US), TransCure bioServices (France), Ozgene Pty Ltd. (Australia), Harbour BioMed (US) among others.

Recent Developments

  • In 2020, GenOway acquired exclusive worldwide rights from Merck for its foundational CRISPR/Cas9 portfolio in the rodent field.
  • In 2020, Taconic entered into an agreement with the University of Texas Medical Branch to distribute humanized ACE2 mice for COVID-19 research.
  • In 2020, The Jackson Laboratory started the production of ACE2 mice to support the research on COVID-19.
  • In 2020, Danaher Corporation acquired GE Healthcare’s Life Sciences business.
  • In 2020, Thermo Fisher launched Orbitrap Exploris 240 and Orbitrap Exploris 120 mass spectrometers.
  • In 2020, Waters Corporation announced the establishment of Immerse Cambridge, a research laboratory in the heart of Cambridges Kendall Square. Immerse Cambridge will serve as a strategic, collaborative space in the community, where Waters can partner with academia and research to accelerate the next generation of scientific advancements.

Report Objectives

  • To define, describe, and measure the global in vivo toxicology market based on product, test type, testing facility, toxicity endpoint, end user, and region
  • To provide detailed information regarding the major factors, such as drivers, restraints, opportunities, and challenges, influencing the growth of the market
  • To strategically analyze the micromarkets1 with respect to individual growth trends, prospects, and contributions to the global in vivo toxicology market
  • To analyze the opportunities in the global in vivo toxicology market for key stakeholders and provide details of the competitive landscape for major market leaders
  • To forecast the size of the market segments with respect to five main regions: North America, Europe, Asia Pacific, Latin America and Middle East Africa
  • To profile the key players and comprehensively analyze their core competencies2 in terms of key developments, product portfolios, and financials
  • To track and analyze competitive developments such as partnerships, agreements, alliances, joint ventures, collaborations, product launches, expansions, acquisitions, grants/funds, and licensing agreements, among others, in the in vivo toxicology market

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