The concept of targeted protein degradation presents revolutionary drug development opportunities and is anticipated to bring about a paradigm shift in modern healthcare. The first targeted protein degrader, called proteolysis targeting chimera (PROTAC), was developed about a decade ago.
Presently, a variety of other such chemical entities and molecular glues are under investigation. In fact, certain pipeline candidates are already in the mid to late-phase trials and are anticipated to soon enter the market.
The USD 3.6 billion (by 2030) financial opportunity within the Target Protein Degradation Market has been analyzed across the following segments:
Type of payment of licensing agreements
- Upfront payments
- Milestone payments
Type of protein degrader
- Degronimids
- PROTACs
- SARDs / SERDs
- Specific BET and DUB inhibitors
- Other protein degraders
Therapeutic area
- Neurodegenerative disorders
- Oncological disorders
- Other therapeutic areas
Route of administration
- Oral
- Intravenous
- Other routes
Key geographical region
- North America
- Europe
- Asia-Pacific
The Targeted Protein Degradation Market: Focus on Therapeutics and Technology Platforms (based on Degronimids, ENDTACs, Epichaperome Inhibitors, Hydrophobic Tags, IMiDs, LYTACs, Molecular Glues, PHOTACs, PROTACs, Protein Homeostatic Modulators, SARDs, SERDs, SNIPERs, and Specific BET and DUB Inhibitors), 2020-2030 report features the following companies, which we identified to be key players in this domain:
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Key Players
- Arvinas
- Captor Therapeutics
- Celgene
- Genetech
- Kymera Therapeutics
- Mission Therapeutics
- Progenra
- Radius Health
- Sanofi Genzyme
- Zenopharm
Table of Contents
- Preface
- Executive Summary
- Introduction
- Current Market Landscape
- Company Profiles
- Clinical Trial Analysis
- KOL Analysis
- Publication Analysis
- Funding and Investment Analysis
- Partnerships and Collaborations
- Market Sizing and Opportunity Analysis
- Executive Insights
- Concluding Remarks
- Appendix 1: Tabulated Data
- Appendix 2: List of Companies and Organizations
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About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector.
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